The Willis Lecture 2003: Evaluating Treatments for Stroke Patients Too Slowly

The Willis Lecture 2003: evaluating treatments for stroke patients too slowly: time to get out of second gear.

T homas Willis was born in 1621, received his classical education and then medical degree from Oxford in 1646, became a highly successful and prosperous physician, and, in 1660, was appointed Professor of Natural Philosophy at the University of Oxford. 1 Although at that time there were no neurologists as such, he coined the word neurology in his Cerebri Anatome: 2 " We should deliver an exact ...

Brain plasticity and stroke rehabilitation. The Willis lecture.

Neuronal connections and cortical maps are continuously remodeled by our experience. Knowledge of the potential capabilityof the brain to compensate for lesions is a prerequisite for optimal stroke rehabilitation strategies. Experimental focal cortical lesions induce changes in adjacent cortex and in the contralateral hemisphere. Neuroimaging studies in stroke patients indicate altered poststro...

Controversies in stroke: past and present. The Willis Lecture.

2014 Thomas Willis Award Lecture: sex, stroke, and innovation.

Thomas Willis Lecture

Over the past few decades, preclinical research on stroke has led to tremendous progress in our basic understanding of the pathophysiological events that follow focal cerebral ischemia. Numerous cellular and molecular targets have been identified for brain protective and restorative therapies, and many of these are highly effective in rodents. The incidence and morbidity and mortality of stroke...